England return to Ashton Gate in Bristol on Saturday to continue their bid for yet another Women's Six Nations Grand Slam title.
The Red Roses beat France in last year's World Cup semifinal at the same venue and will look to extend their winning run to 36 Tests on Saturday.
Wales come into the game with all the work to do following defeats to Scotland and France so far this year.
Here is everything you need to know about the match.
Key details:
Who: England vs. Wales
When: Saturday, April 20 at 2.15 p.m. BST
Where: Ashton Gate, Bristol
Referee: Ella Goldsmith (RA)
Assistant referees: Jess Ling (RA), Beatrice Smussi (FIR)
Television Match Official: Leo Colgan (IRFU)
Where is England vs. Wales being broadcast?
The game will be televised on BBC and BBC Radio 5 Live will have audio commentary. ESPN will also have live updates of the match from Bristol.
Team news:
England:
Forwards: 1. Mackenzie Carson, 2. Amy Cokayne, 3. Sarah Bern, 4. Abi Burton, 5. Delaney Burns, 6. Sadia Kabeya, 7. Marlie Packer, 8. Maddie Feaunati.
Backs: 9. Lucy Packer, 10. Holly Aitchison, 11. Claudia Moloney-MacDonald, 12. Helena Rowland, 13. Megan Jones - captain, 14. Millie David, 15. Ellie Kildunne
Replacements: 16. Connie Powell, 17. Kelsey Clifford, 18. Maud Muir,19. Haineala Lutui, 20. Demelza Short, 21. Flo Robinson, 22. Zoe Harrison, 23. Jess Breach.
Wales:
Starting XV: 1. Gwenllian Pyrs, 2. Kelsey Jones, 3. Sisilia Tuipulotu, 4. Jorja Aiono, 5. Gwen Crabb, 6. Branwen Metcalfe, 7. Bethan Lewis, 8. Bryonie King, 9. Keira Bevan, 10. Lleucu George, 11. Jasmine Joyce, 12. Courtney Keight, 13. Hannah Dallavalle, 14. Seren Singleton, 15. Kayleigh Powell
Replacements: 16. Molly Reardon, 17. Maisie Davies, 18. Donna Rose, 19. Georgia Evans, 20. Alisha Joyce, 21. Seren Lockwood, 22. Jenna De Vera, 23. Catherine Richards